Clinical observation on effect of modified Yanghe Decoction combined with glycocorticoid for treatment of polymyalgia rheumatica / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To observe the effect of modified Yanghe Decoction (YHD) on the dose of glucocorticoid demanded in treating polymyalgia rheumatica (PMR).</p><p><b>METHODS</b>Sixty-one patients with PMR were randomly assigned to two groups, the 32 patients in the treatment group treated with YHD two doses per day combined with prednisone and the 29 patients in the control group treated with prednisone alone. The dosage of prednisone used was started from 20 mg/d and decreased step by step as possible after 2 weeks according to patient's condition. The therapeutic course for them all was 12 weeks.</p><p><b>RESULTS</b>The therapeutic efficacy of PMR in the 32 patients of the treatment group was remission in 9 (28.1%), markedly effective in 15 (46.9%), effective in 7 (21.9%), and ineffective in 1 (3.1%), with the total effective rate of 96.9%; while that for the 29 patients of the control group, the corresponding numbers and percentages were 3 (10.3%), 11 (37.9%), 10 (34.5%), 5 (17.2%), and 82.8%. Compared with the control group, the treatment group can alleviate the activity of PMR more significantly (u = 2.109, P < 0.05) showing a greater and quicker decrease of erythrocyte sedimentation rate (t = 2.957, P < 0.05); and the dosage of prednisone demanded in the treatment group was reduced faster than that in the control group (t = 10.23, P<0.05).</p><p><b>CONCLUSION</b>YHD was helpful to shorten the therapeutic course for PMR, decrease the dosage of glucocorticoid used and raise the therapeutic efficacy.</p>

An experimental study of ultrasound-phoresis of Chinese herb in accelerating fracture healing / 中华物理医学与康复杂志

Objective To explore the effect of uhrasound-phoresis of Chinese herb in the treatment of frac- ture healing on rats.Methods The animal model of femur fracture was established in 36 rats,who were divided in- to 4 groups after operation.The rats in the ultrasound group were given ultrasound treatment daily.The herbal group was given Chinese herb applied on the fracture site.The experimental group was given uhrasound-phoresis of Chinese herb on the site of fracture.The control group was housed without any treatment.All rats were sacrificed at 30 days and the bony callus were harvested and observed with histological anti immunohistoehemical examination.Results The histological examination showed that the appearance of cartilaginous and bony callus in the experimental group were earlier than those in other groups,Immunohistochemical examination showed that the expression of collagenⅠin the experimental group was significantly higher than that in ultrasound group and herbal group(P